Pharmacology Principal Research Associate

Vertex Pharmaceuticals · Boston, MA

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ResearchFull-time$90k–$135kCompany career page

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Role summary

Vertex Pharmaceuticals seeks a Pharmacology Principal Research Associate to conduct independent research evaluating compound effects on disease biology using flow cytometry, cell sorting, and in vivo techniques. The role requires advanced technical expertise in experimental design and execution with rodent and large animal models.

What they're looking for

Bachelor's degree in biological science (minimum); 5+ years experience with bachelor's or 2+ years with master's
Expert-level proficiency in flow cytometry analysis and cell sorting with ex vivo samples
Hands-on experience with in vivo pharmacology techniques including animal handling and dosing
Demonstrated ability to design, execute, and independently interpret complex experiments
Strong analytical skills and solid understanding of biological and immunological principles
Experience performing basic analytical assays such as ELISA on serum and urine samples
Background in muscular dystrophy or cystic kidney disease preferred

What you'll be doing

Design, execute, and interpret in vivo experiments with high degree of independence and technical rigor
Lead flow cytometry analysis and cell sorting workflows for ex vivo samples from rodent and large animal studies
Conduct in vivo procedures including animal handling, dosing, perfusion, biofluid collection, and tissue processing
Perform basic analytical assays including ELISA analysis and statistical analysis of experimental data
Troubleshoot experimental challenges independently, prepare protocols and reports, and present findings at meetings

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