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Sr. Principal Scientist (Sr. Research Scientist)

ICON · Lenexa Kcib

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Role summary

ICON seeks a Senior Research Scientist in Lenexa, Kansas to design and execute complex clinical research studies, with expertise in ligand binding assays and bioanalytical methods. The role involves method development, scientific consultation, mentoring junior staff, and ensuring regulatory compliance in a clinical research organization.

What they're looking for

  • PhD in relevant scientific field with 2+ years CRO experience, or MS/BS with 10+ years laboratory experience
  • Advanced experience in ligand binding assays (ELISA, ECLIA) and pharmacokinetic/pharmacodynamic studies
  • Proficiency with bioanalytical software (SoftMax Pro, Watson) and analytical instrumentation
  • Strong publication record and experience presenting in regulated research fields
  • Expertise in GLP compliance, method validation, and SOP development
  • Excellent cross-functional communication and scientific leadership capabilities

What you'll be doing

  • Design and independently execute ligand binding assay method development experiments and protocols
  • Mentor junior scientists and advise operations teams on assay methodology and troubleshooting
  • Provide scientific input to management and business development on technology investments and assay requirements
  • Lead data review, validation support, and quality assurance for bioanalytical projects
  • Develop rugged, cost-effective assays and communicate project status with internal teams and external clients

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