Sr. Staff Scientist - Protein Sciences R&D

Twist Bioscience · South San Francisco, CA

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Role summary

Twist Bioscience seeks a senior protein scientist with deep expertise in antibody expression, purification, and characterization to lead protein sciences research and development. The role combines hands-on laboratory work with team building and technical roadmap definition for advancing antibody production capabilities.

What they're looking for

Deep hands-on experience designing, expressing, and optimizing monoclonal antibodies
Proven expertise with bispecific antibody architectures and chain pairing control
Demonstrated proficiency with antibody characterization methods (SEC, CE-SDS, BLI/SPR, DSF, DLS)
Strong mechanistic understanding of antibody biology, structure, and expression limitations
Proven track record developing and standardizing antibody generation workflows
Ability to build and lead scientific teams while maintaining bench work

What you'll be doing

Develop small- to medium-scale antibody production workflows across multiple formats and purification methods
Enhance end-to-end antibody development pipeline from construct design through analytics
Build and manage a team of scientists and research associates
Design and execute independent experiments with rigorous data analysis
Establish yourself as subject matter expert and communicate results clearly

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Date posted21 days ago

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