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Senior Scientist I

Cytokinetics · South San Francisco, CA

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ResearchFull-time$162k–$189kCompany career page

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Role summary

Cytokinetics seeks a Senior Scientist to lead small molecule synthesis and process development for cardiovascular drug candidates. The role encompasses synthetic route design, process optimization, scale-up activities, and regulatory support from early development through commercialization.

What they're looking for

  • Ph.D. in Organic Chemistry or related field with 5+ years biotech/biopharma experience
  • M.S. with 8+ years relevant small molecule drug substance development experience
  • Expertise in multi-step organic synthesis and reaction optimization
  • Experience scaling small molecule APIs from laboratory to manufacturing
  • Proficiency in analytical techniques for drug characterization (HPLC, LC-MS, NMR)
  • Familiarity with cGMP regulations and pharmaceutical quality systems
  • Strong problem-solving skills and effective scientific communication abilities

What you'll be doing

  • Design and execute scalable manufacturing routes for small molecule drug substances
  • Optimize synthetic sequences for improved yield, purity, and manufacturability
  • Conduct process characterization studies and establish critical process parameters
  • Characterize process streams and products using analytical techniques
  • Collaborate with CDMO partners on tech transfer and commercial scale-up activities

Privacy & handoff

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Date posted4 days ago
Last source check1 day ago
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