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Scientist, ADC In Vivo Pharmacology

Pfizer · San Diego, CA

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ResearchFull-time$79k–$132kCompany career page

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Role summary

Pfizer seeks a scientist to execute in vivo efficacy and pharmacodynamic studies for antibody-drug conjugate programs within the Oncology Research Unit. The role involves designing and conducting preclinical oncology animal studies, managing study protocols, and collaborating across functional teams to support ADC discovery.

What they're looking for

  • Bachelor's degree in biology, pharmacology, animal science, or related discipline
  • Hands-on experience conducting rodent in vivo studies in pharma, biotech, or CRO settings
  • Proficiency with tumor implantation, measurement, animal monitoring, dosing, and documentation
  • Working knowledge of oncology pharmacology, tumor response assessment, and tolerability concepts
  • Strong attention to detail, protocol adherence, and ability to manage multiple concurrent studies
  • Effective communication and collaborative skills in matrixed scientific environments

What you'll be doing

  • Execute in vivo oncology efficacy and pharmacodynamic studies using syngeneic, cell line-derived, and patient-derived xenograft models
  • Perform tumor measurements, body weight monitoring, test article administration, and biological sample collection
  • Prepare and review study protocols, dosing schedules, randomization plans, and sample collection timelines
  • Maintain accurate study records using electronic data capture systems and coordinate with cross-functional teams
  • Assist with data quality review, graphical summaries, and preliminary interpretation of study results

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