Scientist, ADC In Vivo Pharmacology

Pfizer · San Diego, CA

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ResearchFull-time$79k–$132kCompany career page

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Role summary

Pfizer seeks a scientist to execute in vivo pharmacology studies supporting antibody-drug conjugate programs within the Oncology Research Unit. The role involves designing and conducting preclinical efficacy and tolerability studies using rodent tumor models, with emphasis on technical rigor and animal welfare compliance.

What they're looking for

Bachelor's degree in biology, pharmacology, animal science, cancer biology, or related discipline
Hands-on experience conducting rodent in vivo studies in pharmaceutical, biotech, or CRO settings
Proficiency with tumor implantation, measurement, animal monitoring, dosing, and study documentation
Working knowledge of oncology pharmacology concepts and dose-response assessment
Strong attention to detail, protocol compliance, and ability to manage multiple concurrent studies
Effective written and verbal communication skills for matrixed scientific collaboration

What you'll be doing

Execute in vivo oncology efficacy and pharmacodynamic studies using syngeneic, cell line-derived, and patient-derived xenograft models
Perform tumor measurements, body weight monitoring, clinical observations, test article administration, and sample collection
Prepare and review study protocols, dosing schedules, randomization plans, and study records using electronic data capture systems
Coordinate with project leads, vivarium operations, pathology, and bioanalytical teams to support study execution
Assist with data quality review and preliminary interpretation of in vivo study results

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