Scientist, ADC In Vivo Pharmacology

Pfizer · San Diego, CA

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ResearchFull-time$79k–$132kCompany career page

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Role summary

Pfizer is recruiting a Scientist for its In Vivo Pharmacology group in the Oncology Research Unit to conduct preclinical efficacy, pharmacodynamic, and tolerability studies supporting antibody-drug conjugate and other therapeutic programs. The role involves executing rodent studies, performing dosing and monitoring procedures, and collaborating across functional teams to advance oncology discovery.

What they're looking for

Bachelor's degree in biology, pharmacology, animal science, cancer biology, or related field
Hands-on experience conducting rodent in vivo studies in academic, biotech, pharma, or CRO settings
Proficiency with tumor implantation, measurement, animal dosing, sample collection, and study documentation
Working knowledge of oncology pharmacology concepts and dose-response relationships
Strong attention to detail, organizational skills, and ability to manage multiple concurrent programs
Effective communication and collaborative skills in matrixed scientific environment
Ability to follow protocols precisely and escalate animal welfare or technical concerns

What you'll be doing

Execute in vivo oncology efficacy and pharmacodynamic studies using xenograft, syngeneic, and other tumor models
Perform tumor measurements, body weight monitoring, test article administration via multiple routes, and clinical observations
Conduct routine in vitro tissue culture procedures and support biomarker and dose-response assessments
Prepare and maintain accurate study protocols, randomization plans, and compliant electronic documentation
Coordinate with project leads, vivarium operations, pathology, and translational science teams to ensure efficient study execution

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