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Research Intern (Downstream Processing) - Marlborough, MA

Sartorius · Marlborough, MA

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Role summary

Sartorius seeks a PhD-level research intern to support downstream processing development for extracellular vesicles and viral vectors. The role involves hands-on optimization of purification workflows using tangential flow filtration and chromatography, with direct contributions to nanoparticle process development at the Marlborough, MA site.

What they're looking for

  • PhD candidate in Bioengineering or closely related discipline
  • Hands-on experience with TFF systems at lab or pilot scale
  • Practical knowledge of chromatography techniques (SEC, IEX, affinity)
  • Familiarity with nanoparticle systems such as EVs or viral vectors
  • Experience with analytical tools (NTA, BCA, qPCR, HPLC, SEC-MALS)
  • Strong documentation and organizational skills with SOP experience

What you'll be doing

  • Execute purification protocols for EVs and viral vectors using TFF and chromatography systems
  • Assist in designing and optimizing downstream steps to improve yield, purity, and scalability
  • Operate and maintain TFF and chromatography equipment including setup and troubleshooting
  • Prepare samples, quantify particles using orthogonal methods, and maintain detailed lab documentation
  • Support analytical assays and collaborate with upstream, analytical, and formulation teams
Compensationup to $30/hr

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Date posted4 days ago
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