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Principal Scientist, Drug Discovery

Merck · Rahway, NJ

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ResearchFull-time$170k–$267kCompany career page

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Role summary

Merck seeks a Principal Scientist to lead drug discovery initiatives for animal health, identifying and advancing novel molecular entities and technologies from early concept through proof-of-concept phase. The role requires directing cross-functional research programs while collaborating with internal teams and external partners.

What they're looking for

  • PhD and/or DVM/VMD with board certification in pharmacology
  • Minimum 8 years industry or pharmaceutical research in drug discovery and preclinical in vivo pharmacology
  • Advanced knowledge of pharmacology, disease mechanisms, and preclinical models
  • Expertise in oncology, diabetes, respiratory/immunology, cardiology, pain/inflammation, or reproduction
  • Knowledge of regulatory requirements including GLP, GCP, and GMP
  • Ability to manage multiple projects, budgets, contracts, and timelines independently
  • Strong communication skills and experience preparing executive presentations and patent applications

What you'll be doing

  • Identify new molecular entities and technologies for animal health from internal labs and external partners
  • Lead research programs from ideation through early-stage research and proof-of-concept development
  • Interface with researchers, senior management, and external collaborators across matrix organization
  • Secure resources for research work across medicinal chemistry, pharmacology, pharmacokinetics, and toxicology
  • Manage multiple concurrent projects including budgets and timelines

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