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Associate Principal Scientist, Immunology Discovery

Merck · San Diego (science Park Road), CA

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ResearchFull-time$142k–$224kCompany career page

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Role summary

Associate Principal Scientist position in immunology discovery focused on developing therapies for inflammatory and autoimmune diseases. The role involves leading early-stage programs, designing validation strategies, and advancing candidates from discovery through clinical development.

What they're looking for

  • Ph.D. in immunology, cell biology, or related biomedical science with 5+ years experience
  • Demonstrated experience contributing to or leading discovery-stage programs
  • Expert knowledge of immune-mediated diseases in gastroenterology, rheumatology, or dermatology
  • Proficiency with cell culture, flow cytometry, immunoassays, and molecular biology techniques
  • Strong data analysis skills using Excel, GraphPad Prism, and FlowJo
  • Ability to work independently and lead cross-functional teams through influence and mentorship
  • Excellent communication skills for presenting data and strategies to broad audiences

What you'll be doing

  • Define and drive drug discovery immunology project strategies collaborating across functional areas
  • Lead cross-functional teams advancing therapeutic candidates from early discovery to clinical stage
  • Design, execute and interpret complex in vitro and ex vivo studies aligned with program goals
  • Identify, validate and implement innovative approaches and technologies to enhance program efficiency
  • Mentor less experienced scientists and communicate complex data to stakeholders

Key requirements

Therapeutic area
Immunology

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