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Associate Principal Scientist, Immunology Discovery

Merck · San Diego (science Park Road), CA

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ResearchFull-time$142k–$224kCompany career page

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Role summary

Merck seeks an Associate Principal Scientist in Immunology Discovery to lead early-to-late stage drug discovery programs for inflammatory and autoimmune diseases. The role involves directing cross-functional teams, designing innovative research strategies, and advancing therapeutic candidates from discovery through clinical development in San Diego.

What they're looking for

  • Ph.D. in immunology, cell biology, or related biomedical science with 5+ years experience
  • Demonstrated leadership of early-to-late stage discovery programs in matrixed environments
  • Strong immunology background with knowledge of immune-mediated diseases in gastroenterology, rheumatology, or dermatology
  • Expertise in cell culture, flow cytometry, immunoassays, and molecular biology techniques
  • Proficiency with data analysis tools including Excel, GraphPad Prism, and FlowJo
  • Strong cross-functional collaboration and mentoring abilities
  • Excellent communication of complex data and program strategies to diverse audiences

What you'll be doing

  • Define and execute drug discovery immunology project strategies across multiple programs
  • Lead cross-functional teams to advance therapeutic candidates from early discovery to clinical stage
  • Present program recommendations and strategic decisions to senior governance committees
  • Design, execute, and interpret complex in vitro and ex vivo immunology studies independently
  • Identify and implement innovative approaches and technologies to increase program efficiency and productivity

Key requirements

Therapeutic area
Immunology

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