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Senior Scientist - Automation and HTS – Target Discovery & Biology (TD&B)

Amgen · Thousand Oaks, CA

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Role summary

Senior Scientist role focused on developing automation strategies for functional genomics screening and high-throughput target discovery. The position involves integrating advanced in vitro models, multi-omics profiling, and automation platforms to accelerate biological discovery across therapeutic areas.

What they're looking for

  • Doctorate degree, or Master's with 3+ years functional genomics screening experience, or Bachelor's with 5+ years experience
  • High throughput screening and arrayed CRISPR screening experience preferred
  • Proficiency with automation instrumentation and optimization of complex laboratory equipment
  • Cell culture expertise; iPSC differentiation and complex in vitro model experience preferred
  • Experience with high content imaging assays and automation scheduling software
  • Excellent organizational and communication skills for cross-functional collaboration

What you'll be doing

  • Develop and execute automation pipelines for functional genomic screens in advanced in vitro models
  • Convert manual laboratory protocols to automated platforms in 96-well and 384-well formats
  • Optimize high content imaging assays and microscopy parameters for screening applications
  • Identify and implement emerging automation and imaging technologies to enhance discovery platforms
  • Lead team efforts and foster collaborative culture within cross-functional discovery group

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Date posted1 day ago
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