Sr Scientist, Drug Metabolism
Gilead Sciences · Foster City, CA
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Role summary
Gilead Sciences seeks a senior scientist in drug metabolism to provide pharmacokinetic and PK/PD modeling expertise across discovery and development programs. The role involves designing mechanistic models, guiding nonclinical study strategies, and collaborating with interdisciplinary teams to inform regulatory submissions and business decisions. Requires a Ph.D., 5+ years of industry experience in quantitative modeling, and proficiency with industry-standard software platforms.
What they're looking for
- Ph.D. in pharmacokinetics, drug metabolism, pharmaceutics, or related life science field
- 5+ years post-graduate industry experience in quantitative modeling of PK/PD
- Strong foundation in pharmacokinetic and pharmacodynamic principles with mathematical modeling ability
- Proficiency with modeling software: Phoenix/WinNonlin, MATLAB/SimBiology, GastroPlus, R, or equivalent
- Demonstrated expertise designing and interpreting complex mechanistic PK/PD and multi-compartmental models
- Hands-on experience applying AI in model-building and workflow automation
- Track record of external visibility through publications, presentations, or professional involvement
What you'll be doing
- Provide PK and PK/PD modeling guidance for project teams across discovery and development phases
- Design, implement, and validate complex models to address translational questions and predict first-in-human exposures
- Drive quantitative DMPK strategy through collaboration with interdisciplinary teams and stakeholders
- Develop and refine modeling workflows for nonclinical studies using simulation-based optimization approaches
- Support regulatory submissions and participate in business development and licensing evaluations
Key requirements
- Therapeutic area
- Metabolic
Privacy & handoff
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