Sr. Director, Pharmacology

Vertex Pharmaceuticals · San Diego, CA

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ResearchFull-time$239k–$358kCompany career page

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Role summary

Vertex Pharmaceuticals seeks a senior scientific leader to direct pharmacology strategy and manage assay development for drug discovery programs in San Diego. The role involves leading a team to design and execute in vitro and in vivo studies supporting therapeutic optimization, while contributing to site research direction and cross-functional initiatives.

What they're looking for

Ph.D. in Pharmacology or related field with post-doctoral industry experience
12+ years drug discovery experience with demonstrated early-stage excellence
Proven management of functional or cross-functional research groups including Ph.D. scientists
Deep expertise in in vitro/in vivo assay design, execution, and interpretation
Extensive ion channel pharmacology and mechanism-of-action study experience
Track record developing innovative translational models predicting human efficacy
Strong communication skills and ability to influence matrixed organizations

What you'll be doing

Direct pharmacology strategy and provide scientific, operational, and people leadership across multiple programs
Manage team responsible for assays assessing drug potency, efficacy, and mechanism of action
Set priorities, allocate resources, manage budgets, hiring, and ensure company goal achievement
Drive study planning, data quality, regulatory documentation, publications, and patents
Partner cross-functionally to influence research direction, reduce project risk, and advance solutions

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