Senior Director, Process Development – CGT Drug Product
Vertex Pharmaceuticals · Boston, MA
CMCFull-time$230k–$345kCompany career page
The apply link worked recently (not employer-confirmed).
Role summary
Vertex Pharmaceuticals seeks a Senior Director to lead drug product process development for cell and gene therapies at their Boston R&D site. The role encompasses formulation, cryopreservation, fill-and-finish, and commercialization strategy across autologous and allogeneic modalities, requiring deep technical expertise and cross-functional leadership.
What they're looking for
- Deep experience in drug product development for cell and gene therapies
- Demonstrated expertise with autologous and/or allogeneic therapy modalities
- Strong biologics drug product background applicable to advanced therapies
- Proven ability to lead technical teams in matrixed environments
- Executive presence with strategic judgment and cross-stakeholder influence
- Experience with formulation, cryopreservation, fill-and-finish process development
- Knowledge of Quality by Design principles and regulatory CMC strategies
What you'll be doing
- Establish and execute integrated drug product process development strategy from clinical development through commercialization
- Lead formulation, cryopreservation, and aseptic fill-and-finish process development and optimization
- Drive process characterization, risk assessment, design space definition, and control strategy using Quality by Design
- Oversee technology transfer of drug product processes to internal and external manufacturing partners
- Build, lead, and develop high-performing team of scientists and engineers across drug product operations
Privacy & handoff
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