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Scientist, Upstream Process Development

Johnson & Johnson · Spring House, PA

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Role summary

Johnson & Johnson seeks a scientist to support upstream process development for lentiviral in vivo therapeutic programs. The role focuses on cell culture optimization, bioreactor studies, and process characterization across early-stage through clinical development.

What they're looking for

  • BS or MS in Chemical Engineering, Biochemical Engineering, Biological Sciences, or Biotechnology
  • 2-4+ years of mammalian cell culture process development experience
  • Hands-on bioreactor operation and media optimization expertise
  • Experience with Ambr® 250 high-throughput bioreactor systems
  • Proficiency in data analysis, experimental design, and technical documentation
  • Strong written and verbal communication with cross-functional collaboration ability

What you'll be doing

  • Design and execute upstream process development studies for lentiviral therapeutic products
  • Perform cell culture experiments using shake flasks, bioreactors, and high-throughput systems
  • Develop and optimize fed-batch and perfusion processes for productivity and manufacturability
  • Apply experimental design and data analytics to support process understanding and decision-making
  • Author technical reports, protocols, and regulatory documentation; collaborate across functional teams

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