Scientist II, Upstream Polysaccharide Process Development

Vaxcyte · San Carlos, CA

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Role summary

Vaxcyte seeks a Scientist II to design and execute upstream fermentation studies for polysaccharide vaccine manufacturing. The role involves process development, optimization, and troubleshooting using microorganisms, with significant hands-on laboratory work and cross-functional collaboration.

What they're looking for

Practical laboratory experience in microbial fermentation and upstream process development
Proficiency with bioreactor systems and fermentation equipment operation
Knowledge of statistical design of experiments and process optimization methods
Strong experimental design, data interpretation, and technical decision-making skills
Experience with microbiology and analytical testing in bioprocess contexts
Ability to author technical documents and present scientific results

What you'll be doing

Design, execute, and analyze upstream polysaccharide fermentation studies for process development and optimization
Develop and troubleshoot fermentation processes to improve yield, quality, and consistency
Perform bioreactor operations, maintenance, troubleshooting, and automation script development
Investigate anomalous results through root-cause experimentation and structured problem-solving
Lead assigned project activities and provide technical guidance to junior team members

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