Scientist I
Cytokinetics · South San Francisco, CA
ResearchFull-time$135k–$158kCompany career page
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Role summary
Cytokinetics seeks a synthetic and medicinal chemist to design and synthesize novel small-molecule drug candidates for cardiovascular diseases. The role involves hands-on chemistry work within multidisciplinary teams, applying medicinal chemistry principles and computational tools to advance discovery programs toward clinical development.
What they're looking for
- Ph.D. in Organic or Medicinal Chemistry, or M.S. with relevant industry experience
- Demonstrated expertise in organic synthesis, chromatographic purification, and analytical characterization (NMR, MS, HPLC)
- Proficiency in multi-parameter optimization and hypothesis-driven problem-solving
- Ability to apply computational chemistry tools to support compound design
- Track record of scientific achievement and peer-reviewed publications
- Strong organizational skills, attention to detail, and excellent communication abilities
What you'll be doing
- Synthesize drug candidates and focused libraries to advance optimization programs toward clinical development
- Design next-generation compounds integrating medicinal chemistry, DMPK, and physicochemical principles
- Develop and apply purification methods for synthesized compounds using chromatographic techniques
- Integrate biology and DMPK feedback into design decisions using structure-based and computational approaches
- Communicate research progress within cross-functional project teams and maintain thorough experimental documentation
Privacy & handoff
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