Radioconjugate Scientist - IHC
AstraZeneca · Longwood Road South, Canada
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Role summary
Fusion Pharmaceuticals (AstraZeneca) seeks a scientist to develop and execute histology and immunohistochemistry assays supporting early-stage radioconjugate drug discovery. The role involves independent optimization of tissue-based workflows, imaging analysis, and radiolabeled sample handling in a Hamilton, Ontario facility.
What they're looking for
- BSc or MSc in Biology, Biomedical Sciences, Histology, Pathology, or equivalent with hands-on laboratory experience
- Extensive practical experience with paraffin embedding, microtomy, IHC, and immunofluorescence
- Proven experience operating automated staining platforms for IHC and IF assays
- Strong tissue imaging and quantitative image analysis skills; HALO platform experience preferred
- Demonstrated troubleshooting, data interpretation, and scientific communication abilities
- Ability to work independently while collaborating across multidisciplinary teams
- Willingness to become trained in autoradiography and radiolabeled tissue handling workflows
What you'll be doing
- Develop, optimize, and validate end-to-end histology workflows including tissue processing, embedding, sectioning, and staining
- Independently operate and troubleshoot automated IHC and IF platforms with routine maintenance
- Perform quantitative image analysis using digital pathology software and correlate biomarker data with radiopharmaceutical distribution
- Handle radiolabeled tissue samples following radiation safety procedures and perform tissue-based radiopharmaceutical imaging
- Maintain detailed experimental documentation, communicate results across teams, and ensure compliance with GLP and safety standards
Privacy & handoff
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