Principal Scientist (Director), Translational Medicine - Infectious Diseases
Merck · South San Francisco (grand Ave), CA +3 more
ResearchFull-time$260k–$410kCompany career page
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Role summary
Merck seeks a physician-scientist to lead translational medicine and early clinical development for infectious disease therapeutics. The role spans target identification through clinical proof-of-concept, requiring expertise in bridging discovery research with human studies and regulatory advancement.
What they're looking for
- MD or MD/PhD degree
- Strong background in clinical translational research
- Expertise in infectious disease and anti-infective development
- Experience leading early-phase clinical development programs
- Knowledge of clinical pharmacology and biomarker strategy
What you'll be doing
- Partner with discovery teams to identify and validate novel infectious disease targets using clinical data
- Lead early clinical development strategy from preclinical stage through Phase 2 proof-of-concept studies
- Design and execute clinical pharmacology studies across all development phases including drug-drug interactions
- Develop biomarker validation strategies through experimental medicine and cross-functional collaboration
- Provide regulatory and scientific support for clinical trial design and filing preparation
Key requirements
- Therapeutic area
- Infectious Disease
Privacy & handoff
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