Principal Engineer, Pharmaceutical Development
Nurix Therapeutics · Brisbane, CA
RoleLantern re-checked this role's application link recently and it was active — the employer has not confirmed it directly.
Role summary
Principal Engineer leading pharmaceutical development for small-molecule drug products at late-stage clinical and commercial programs. Responsible for process development, CDMO scale-up, technology transfer, and regulatory compliance to support manufacturing operations and patient access.
Where this listing comes from
This listing was compiled by RoleLantern from the employer's publicly available posting on Greenhouse, captured and rephrased by RoleLantern using automated (AI) tools on 2026-10-06 (originally posted 2026-10-05). It was not submitted or confirmed by the employer through RoleLantern. Details may be inaccurate, incomplete, outdated, or no longer available; please confirm with the employer's official posting before applying.
What they're looking for
- Ph.D. chemical engineering or related field with 8+ years late-phase small-molecule drug product development
- Extensive GMP oral solid dose manufacturing experience (spray drying, tableting, encapsulation, scale-up, validation)
- Proven third-party CDMO management including tech transfer, QBD, DOE studies, clinical and commercial production
- Deep knowledge of cGMP, ICH, FDA, and EMA guidelines and regulatory requirements
- Strong internal and external collaboration and communication skills
- Ability to travel up to 25% and work in fast-paced, multitasking environment
What you'll be doing
- Lead engineering and process optimization for drug product manufacturing and CDMO scale-up activities
- Manage equipment engineering and operations at drug product CDMOs including troubleshooting and process validation
- Coordinate across CDMOs, QA, Chemical Development, and Supply Chain for timely lot manufacture and release
- Write and review CMC sections for regulatory filings including INDs and NDAs
- Provide on-site support and performance monitoring of manufacturing KPIs across facilities
Privacy & handoff
This role links to Nurix Therapeutics's own application system. RoleLantern records your interest and checks the link, but the application happens on the employer's site and status updates may not come back to us. Clicking apply does not mark you as applied automatically.