Associate Scientist, Post Doc Fellow- Quantitative Biosciences Early Discovery

Merck · Rahway, NJ

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ResearchFull-time$82k–$92kCompany career page

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Role summary

Postdoctoral fellowship in quantitative biosciences focused on chemically induced proximity and drug discovery. Candidates will design and execute research using biophysical, biochemical, and computational approaches to investigate protein interactions and advance early-stage drug discovery under senior mentorship.

What they're looking for

Ph.D. in biochemistry, biophysics, pharmacology, structural biology, or related discipline (or completion by spring 2027)
Hands-on expertise with quantitative biophysical methods (SPR, ITC, MST, BLI, fluorescence assays)
Proficiency in recombinant protein design, expression, and chromatographic purification
Working knowledge of biological NMR spectroscopy and/or structural biology techniques
Ability to analyze and interpret protein structures using molecular modeling software
First-author publications and conference presentations demonstrating scientific productivity
Strong written and verbal communication skills with collaborative mindset

What you'll be doing

Design and execute novel methodologies to interrogate chemically induced proximity systems under senior mentorship
Integrate biophysical, biochemical, and structural techniques to investigate macromolecular complexes and protein interactions
Develop independent research agenda from hypothesis generation through mechanistic validation
Collaborate with computational teams to integrate modeling workflows with experimental investigations
Communicate research findings through internal presentations, conferences, and lead-author publications

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