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Associate Scientist Discovery Proteomics

Amgen · South San Francisco, CA

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Role summary

This role involves developing and applying liquid chromatography-tandem mass spectrometry proteomics workflows to support early-stage drug discovery. The Associate Scientist will execute quantitative proteomic experiments, operate LC-MS instruments, analyze data, and collaborate with cross-functional teams to generate high-quality results for target discovery and biomarker studies.

What they're looking for

  • Master's degree, or Bachelor's with 2 years scientific experience
  • Bachelor's, Master's, or PhD in analytical chemistry, biochemistry, or related discipline
  • Hands-on experience with proteomic sample preparation
  • Proficiency with Proteome Discoverer, Spectronaut, DIA-NN, or similar software
  • Ability to troubleshoot LC-MS instrumentation and assess data quality
  • Experience with automated sample-preparation platforms such as Tecan or Hamilton

What you'll be doing

  • Execute and optimize quantitative proteomic workflows including sample preparation and mass spectrometry acquisition
  • Prepare samples from cell lines using protein enrichment and proximity labeling methods
  • Operate LC-MS systems, perform maintenance, and troubleshoot instrument issues
  • Process proteomic data using analysis software and collaborate on interpretation
  • Communicate experimental progress and results to cross-functional project teams

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RoleLantern checkedNeeds clarity
Date posted45 days ago
Last source check1 day ago
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