Senior Scientist - PKDM-BA

Amgen · South San Francisco, CA

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Role summary

Senior Scientist position at Amgen focused on designing and executing biological and biophysical experiments to understand ADME properties of large molecule therapeutics. Lab-based role emphasizing assay and technology development for drug discovery and early development programs.

What they're looking for

PhD, PharmD, or MD; or Master's degree with 3+ years related experience; or Bachelor's degree with 5+ years related experience
PhD or MS in immunology, cell biology, biochemistry, biophysics, or equivalent field
2+ years protein therapeutics drug discovery and development experience in biotech industry
Expertise evaluating protein-protein interactions using modern biophysical analytical techniques
Proficiency in protein biochemistry and cell biology techniques including assay development and optimization
Strong communication and interpersonal skills with ability to thrive in fast-paced environment

What you'll be doing

Design and execute biological and biophysical experiments to characterize ADME properties of large molecule therapeutics
Develop and optimize assays and technologies to define mechanisms of in vivo clearance and biodistribution
Interpret experimental data and communicate results to project team members
Maintain detailed electronic laboratory notebook records of experimental results
Develop and execute department strategy as PKDM project representative for drug candidate teams

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