Senior Scientist, Culture Process Development

Pfizer · Andover, MA

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CMCFull-time$94k–$156kCompany career page

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Role summary

Senior Scientist position in Upstream Process Development focused on designing and optimizing manufacturing processes for recombinant proteins across early- and late-phase clinical trials. The role involves bench-top bioreactor experiments, technology transfer, and regulatory documentation to ensure scalable, high-productivity processes.

What they're looking for

PhD with 0-3 years industry experience, or Master's with 7+ years, or Bachelor's with 9+ years in relevant engineering or life sciences field
Demonstrated experience developing scalable mammalian cell culture processes for therapeutic production
Knowledge of metabolic pathways, process kinetics, and scale-up/scale-down methodologies
Proficiency in aseptic technique, experimental design, data analysis, and interpretation
Strong written and oral communication skills with ability to work independently and collaboratively
Self-motivated with demonstrated ability to drive innovation and solve complex technical problems
Capability to manage multiple priorities in fast-paced, matrixed organizational environment

What you'll be doing

Design and execute laboratory experiments in scale-down bioreactors to develop robust, scalable manufacturing processes
Serve as upstream technical lead and facilitate technology transfer to pilot and commercial manufacturing facilities
Document data in electronic lab notebooks and author technical reports for regulatory submissions
Contribute to design of experiments discussions and provide technical support during manufacturing campaigns
Occasionally work weekends to perform cell culture maintenance and sampling tasks

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