Postdoctoral Scholar, Translational PK (Pharmacokinetics)/PD (Pharmacodynamics) and Investigative Toxicology (TPPIT)
Johnson & Johnson · La Jolla, CA
ResearchFull-time$79k–$128kCompany career page
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Role summary
Johnson & Johnson seeks a postdoctoral scholar to lead a translational research program investigating oral bioavailability barriers of proximity-inducing therapeutics such as PROTACs and molecular glues. The two-year fellowship involves developing in vitro intestinal models, conducting mechanistic studies, and establishing predictive platforms to guide rational drug design.
What they're looking for
- PhD in Pharmaceutical Sciences, Biology, Biochemistry, Pharmacology, or related field
- Track record of peer-reviewed publications, patents, and/or scientific presentations
- Demonstrated ability to independently design, execute, and interpret in vitro studies
- Strong oral and written communication skills
- Independent thinking with ability to collaborate effectively in matrixed environments
- Keen interest in practical troubleshooting and experimental problem-solving
What you'll be doing
- Develop translatable in vitro permeability models to understand PROTAC and proximity inducer absorption
- Evaluate lymphatic absorption and intestinal secretion using mechanistic in vivo studies and PBPK modeling
- Integrate experimental data with computational modeling to identify molecular design principles
- Communicate results and recommendations to team members, partners, and collaborators
- Disseminate findings through internal presentations and high-impact journal publications
Privacy & handoff
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