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Director, Project Toxicologist, Safety Sciences China

AstraZeneca · Shanghai Jing'an

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Role summary

AstraZeneca's Safety Sciences China group seeks a Director-level Project Toxicologist to provide non-clinical safety expertise for drug discovery and development programs. The role combines regulatory toxicology strategy, cross-functional collaboration across therapeutic areas and drug modalities, and integration of preclinical safety assessments into global development pathways.

What they're looking for

  • PhD and/or DABT in Toxicology, Pharmacology, Cell Biology, Pathology, or related discipline
  • Extensive project toxicology or investigative toxicology experience in pharma, biotech, or CRO settings
  • Demonstrated ability to deliver toxicology programs supporting IND regulatory filings
  • Proficiency across small and large molecule modalities and relevant therapeutic areas
  • Fluent in English and Mandarin with cross-cultural awareness of China, EU, UK, and US environments
  • Skilled application of in vitro, in silico, and in vivo safety prediction methodologies

What you'll be doing

  • Lead design of regulatory and investigative toxicology studies to assess and mitigate modality- and target-related safety risks
  • Serve as core member of drug project teams, providing data-driven toxicology recommendations for discovery and development decisions
  • Conduct strategic toxicology assessments for in-licensing evaluations and external collaborations
  • Communicate integrated safety risk assessments to governance bodies and regulatory submissions
  • Advance expertise in emerging safety science technologies including organ-on-chip, imaging, and omics platforms

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