Biomarkers Senior Research Lab Scientist (Ligand Binding Assays)
Vertex Pharmaceuticals · Boston, MA
DiagnosticsFull-time$120k–$180kCompany career page
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Role summary
Vertex Pharmaceuticals seeks a senior research scientist to develop and optimize biomarker assays for clinical trials, focusing on ligand binding assays. The role involves designing experiments to identify and characterize novel biomarkers in human samples, troubleshooting technical challenges, and collaborating across multidisciplinary teams in a fast-paced environment.
What they're looking for
- Ph.D. with 2–5 years post-doctoral experience, or Master's with 5+ years, or Bachelor's with 8+ years
- Hands-on experience developing ligand binding assays for translational or clinical applications
- Demonstrated experience validating assays with knowledge of GLP and GCP standards
- Strong expertise in molecular biology and cell biology techniques
- Extensive method development experience in immunoassays and ELISA
- Proficiency in Western blot, protein labeling, and data interpretation
- Excellent communication skills and proven ability to work independently in multidisciplinary teams
What you'll be doing
- Design and execute method development for biomarker assays intended as clinical trial endpoints
- Evaluate feasibility and measurement strategies for novel biomarkers in human biofluids and tissues
- Troubleshoot technical challenges across assay development, validation, and implementation
- Evaluate external CROs and support assay transfer and validation with vendors
- Generate, analyze, and present experimental data to stakeholders and project teams
Privacy & handoff
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