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Biomarkers Research Lab Scientist (Ligand Binding Assays)

Vertex Pharmaceuticals · Boston, MA

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DiagnosticsFull-time$102k–$154kCompany career page

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Role summary

Vertex Pharmaceuticals seeks a Biomarkers Research Lab Scientist to develop and optimize ligand binding assays supporting clinical trials. The role involves hands-on laboratory work characterizing biomarkers in human samples, performing validation experiments, and collaborating across teams to advance clinical biomarker studies.

What they're looking for

  • Ph.D. with 0–3 years post-doctoral experience, or Master's with 3+ years, or Bachelor's with 6+ years
  • Hands-on experience developing ligand binding assays for translational or clinical applications
  • Strong laboratory expertise in molecular and cell biology techniques
  • Proficiency in immunoassays, ELISA, Western blotting, and protein quantification
  • Demonstrated data interpretation and scientific presentation skills
  • Effective communication and ability to work in multidisciplinary teams

What you'll be doing

  • Develop and optimize biomarker assays for clinical studies through experimental design and execution
  • Characterize biomarkers in human biofluids and tissues and evaluate assay feasibility
  • Perform mock validation experiments and generate data packages supporting assay readiness
  • Support assay transfer to external laboratories and CROs with technical handoff and troubleshooting
  • Analyze results and present findings to internal stakeholders and project teams

Privacy & handoff

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