Staff Software Engineer, Imaging
Insitro · South San Francisco, CA
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Role summary
Insitro seeks a Staff Software Engineer to architect and scale computer vision and machine learning infrastructure for high-throughput imaging workflows in drug discovery. The role involves designing platform capabilities, hardening production pipelines, and partnering with scientists and ML teams to integrate imaging and automation into validated screening systems. Based in South San Francisco with 8+ years of Python development and ML platform experience required.
What they're looking for
- 8+ years building and operating production software and high-throughput data pipelines in Python
- Designed, built, and deployed scientific computing pipelines for large-scale imaging or high-dimensional datasets
- Hands-on experience with Python-first ML stack, distributed compute, and workflow orchestration tools
- Track record owning complex systems from architecture through production operation
- Ability to translate research needs into practical, scalable software solutions
What you'll be doing
- Design and scale platform capabilities for running and interpreting ML-powered high-content imaging screens
- Build tools and interfaces for data exploration, quality assessment, and visualization of experimental data
- Scale imaging and ML workflows from research prototypes to systems processing millions of images daily
- Establish and maintain data integrity, lineage tracking, reproducibility, and observability practices
- Partner with lab scientists, ML scientists, and microscopy teams to translate experimental needs into technical solutions
Privacy & handoff
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