Sr. Scientist, Assay Development - Neuroscience Biomarker Discovery
Merck · Boston (MA Parcel B Laboratory), MA
DiagnosticsFull-time$106k–$167kCompany career page
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Role summary
Senior Scientist position in neuroscience biomarker discovery at Merck's Boston laboratory. Responsible for designing, developing, and executing high-dimensional assays to support biomarker strategies in Alzheimer's, Parkinson's, and pain programs from preclinical to clinical stages.
What they're looking for
- Master's degree in molecular biology, biochemistry, neuroscience, immunology, or related field with 6+ years industry experience, or PhD with relevant hands-on experience
- Demonstrated expertise in biomarker assay development and implementation in large-scale human cohorts and preclinical studies
- Hands-on proficiency in ultra-sensitive, multiplexed immunoassays and Next-Generation Sequencing workflows
- Proven experience designing and implementing laboratory automation tools and liquid handlers for high-throughput assay scaling
- Knowledge of clinical assay validation parameters and regulatory guidelines including FDA and ICH standards
- Strong oral and written communication skills with ability to work effectively in cross-functional teams
What you'll be doing
- Plan, design, execute, and deliver high-quality biomarker datasets from human and preclinical samples supporting neuroscience pipeline programs
- Lead design, development, and qualification of fit-for-purpose biomarker methods including immunoassays and high-plex proteomic platforms
- Collaborate with data scientists to ensure automated workflows produce high-fidelity data suitable for modeling and multi-omics integration
- Identify, pilot, and implement novel high-throughput methodologies for biomarker discovery including robotic automation and single-cell sequencing
- Summarize and communicate data results with internal and external partners to support pipeline governance decisions
Key requirements
- Therapeutic area
- Neuroscience
Privacy & handoff
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