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Senior Manager, IT Operations

Pacific Biosciences · Menlo Park, CA

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IT & SoftwareFull-time$170k–$256kCompany career page

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Role summary

Pacific Biosciences seeks a Senior Manager for IT Operations to lead end-user support, infrastructure management, vendor relations, and change control across the organization. This hands-on role owns the operational core of IT, spanning help desk, networks, data centers, cloud services, and compliance-driven change management in a regulated biotech environment.

What they're looking for

  • Proven experience managing IT help desk, infrastructure, and operations teams
  • Expertise in enterprise network, server, storage, and hybrid cloud infrastructure
  • Demonstrated vendor management and contract negotiation experience
  • Knowledge of IT change management, ITSM frameworks, and incident response
  • Experience in regulated environments (GxP, ISO 13485, ISO 9001) or audit-driven compliance
  • Strong project portfolio management and business case development skills
  • Ability to define and track SLAs, metrics, and service-level performance

What you'll be doing

  • Manage day-to-day help desk operations, SLAs, and end-user support team across all sites
  • Own infrastructure reliability, capacity planning, and lifecycle management for networks, servers, and cloud services
  • Lead IT vendor portfolio sourcing, evaluation, contracting, and performance management
  • Chair change advisory board and enforce change management for regulated systems and audit compliance
  • Establish IT project portfolio intake, prioritization, and executive status reporting mechanisms

Privacy & handoff

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Date posted2 days ago
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