Senior Manager, Commercial Manufacturing, Drug Substance
Revolution Medicines · Redwood City, CA
RoleLantern re-checked this role's application link recently and it was active — the employer has not confirmed it directly.
Role summary
Revolution Medicines seeks a Senior Manager, Commercial Manufacturing, Drug Substance to lead API manufacturing oversight across external partners. This role manages process validation, supply strategy, lifecycle activities, and cross-functional collaboration to ensure compliant, reliable commercial operations for small molecule drug substances.
What they're looking for
- Extensive experience in commercial pharmaceutical API manufacturing operations
- Strong knowledge of process validation, CPV, and regulatory compliance requirements
- Technical expertise in small molecule drug substance manufacturing
- Experience managing external manufacturing partners and CDMOs
- Cross-functional leadership and communication across quality, regulatory, and supply chain
- Demonstrated capability in process robustness, scale-up, and technology transfer
- Strategic planning and risk mitigation in supply chain management
What you'll be doing
- Oversee commercial drug substance manufacturing including PPQ, CPV, and capacity planning activities
- Develop and execute manufacturing capacity strategies aligned with commercial demand forecasts
- Identify and mitigate manufacturing, supply, quality, compliance, and business risks
- Support CDMO selection, onboarding, technology transfer, and technical oversight at external sites
- Write, review, and approve technical documentation including protocols, reports, and regulatory submissions
Privacy & handoff
This role links to Revolution Medicines's own application system. RoleLantern records your interest and checks the link, but the application happens on the employer's site and status updates may not come back to us. Clicking apply does not mark you as applied automatically.