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Senior Director, Oncology Clinical Intelligence & Evidence

AstraZeneca · Cambridge Kendall SQ, MA

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Clinical OperationsFull-timeCompany career page

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Role summary

Senior Director role leading clinical intelligence and real-world evidence strategy for lung and head-and-neck cancer portfolios at AstraZeneca. Responsible for setting evidence priorities, translating portfolio needs into scientific programs, and guiding multidisciplinary teams to generate decision-ready insights across development and commercialization.

What they're looking for

  • Demonstrated leadership of cross-functional scientific or clinical strategy teams
  • Deep expertise in clinical trial design, evidence generation, and real-world data methodology
  • Strong understanding of oncology development, biomarker strategy, and regulatory pathways
  • Ability to frame complex scientific questions and distinguish causal from predictive objectives
  • Experience translating business priorities into scientific programs and evidence agendas
  • Familiarity with advanced analytics, machine learning applications, or AI in clinical contexts

What you'll be doing

  • Set strategic direction for clinical intelligence and RWE generation across lung and HNSCC therapeutic area
  • Identify high-value evidence opportunities and translate portfolio priorities into focused research agendas
  • Originate and prioritize scientific programs addressing patient selection, treatment heterogeneity, and regulatory confidence
  • Lead multidisciplinary teams including strategy leads, evidence product leads, and data scientists
  • Establish evidence priorities and provide scientific guidance to clinical development, regulatory, and commercial functions

Key requirements

Therapeutic area
Oncology

Privacy & handoff

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Date posted6 days ago
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