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Scientist, In Vivo Process Development Downstream

Gilead Sciences · Philadelphia, PA

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CMCFull-time$133k–$172kCompany career page

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Role summary

Kite Pharma seeks a scientist to design and optimize downstream purification processes for lentivirus manufacturing. The role involves applying advanced chemistry and engineering principles to develop scalable, cost-effective processes while supporting manufacturing scale-up and mentoring colleagues.

What they're looking for

  • B.S. with 6+ years, M.S. with 4+ years, or Ph.D./PharmD in science or engineering
  • Hands-on proficiency with downstream unit operations for large biomolecules such as chromatography and filtration
  • Sound understanding of bioprocess scale-up principles for large biomolecules
  • Working knowledge of cGMP principles
  • Proficiency in Microsoft Office and data analysis software such as JMP or GraphPad
  • Strong collaboration, verbal, and written communication skills
  • Excellent organization and problem-solving abilities with attention to detail

What you'll be doing

  • Design and optimize scalable, safe, and cost-effective downstream lentivirus manufacturing processes
  • Develop technical solutions to complex problems using advanced scientific and engineering principles
  • Support manufacturing activities and process optimization at scale to improve performance and scalability
  • Manage laboratory operations including work planning, documentation, and safety compliance
  • Train, mentor, and guide colleagues on technical skills and process execution troubleshooting

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