Scientist I/II, Functional Genomics

Xaira Therapeutics · South San Francisco, CA

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Role summary

Xaira Therapeutics seeks a Scientist I/II in functional genomics to develop and scale organoid-based model systems for CRISPR screening and genotype-phenotype discovery. The role combines hands-on experimental work with cross-functional collaboration across computational biology and AI/ML teams to advance drug discovery capabilities.

What they're looking for

Ph.D. in Molecular Biology, Genetics, Cell Biology, or related field
0-4 years industry or postdoctoral research experience
Hands-on expertise developing and maintaining organoid model systems
Experience with CRISPR-based genetic perturbation approaches in 3D systems
Familiarity with high-throughput screening adaptation and automation methods
Strong troubleshooting and protocol optimization abilities
Excellent written and verbal communication skills

What you'll be doing

Develop, implement, and scale organoid-based screening systems for functional genomics
Establish and optimize organoid culture protocols across tissue types with rigorous quality control
Drive innovation in experimental workflows and CRISPR screening methodologies
Collaborate with computational and AI/ML teams to analyze and interpret large-scale datasets
Independently manage multiple projects and mentor junior research staff

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Date posted2 days ago

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