Scientist, Cell Engineering
Colossal Biosciences · Dallas, TX
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Role summary
Colossal Biosciences seeks a Scientist in Dallas to derive and characterize primary cell lines from non-model organisms, perform gene editing, and conduct cellular assays. The role supports the Cell Engineering team in optimizing cell lines for downstream applications.
What they're looking for
- PhD in biological sciences, stem cell biology, genetics, or related field; BS/MS with significant relevant experience considered
- 4+ years hands-on mammalian cell culture expertise
- Expert knowledge of primary cell derivation, culture, propagation, and biobanking
- Proficiency with CRISPR gene editing and multiple delivery methods including transfection and electroporation
- Experience with flow cytometry, immunostaining, and confocal microscopy
- Microdissection experience and strong aseptic technique
- Strong written and oral communication with creative problem-solving ability
What you'll be doing
- Isolate, expand, and maintain high-quality primary cell cultures from diverse non-model animal tissues
- Design and execute experiments to generate and characterize primary cells, develop functional assays, and assess workflows
- Assess workflow efficiency through cellular assays and NGS sequencing approaches
- Collaborate with genome engineers to screen, validate, and prepare cell lines for SCNT
- Prepare project reports and presentations documenting progress and findings
Privacy & handoff
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