Principal Scientist, Translational Clinical Biomarkers
Merck · Upper Gwynedd, PA +3 more
Clinical OperationsFull-time$191k–$300kCompany career page
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Role summary
Principal Scientist position leading translational and clinical biomarker strategies across cardiovascular, metabolic, infectious disease, and vaccine development programs. The role involves designing decision-centric biomarker approaches, partnering with cross-functional teams, and translating complex scientific findings into actionable recommendations for program advancement.
What they're looking for
- Ph.D., M.D., or equivalent advanced degree in translational medicine, biomarker science, or drug development
- Significant experience developing and executing translational or clinical biomarker strategies in drug or vaccine development
- Scientific expertise in cardiovascular disease, metabolic disease, infectious diseases, vaccines, immunology, or related areas
- Ability to lead cross-functional scientific work in matrix environments and influence without direct authority
- Strong analytical and problem-solving skills with ability to synthesize complex datasets into decision-oriented conclusions
- Working knowledge of biostatistics, bioinformatics, quantitative sciences, and multidimensional biomarker data analysis
- Excellent written and verbal communication skills for scientific strategy communication to stakeholders
What you'll be doing
- Develop and lead integrated biomarker strategies across cardiovascular/metabolic and infectious disease/vaccine programs with cross-functional teams
- Translate disease biology and therapeutic mechanisms into translational hypotheses and fit-for-purpose biomarker approaches
- Serve as biomarker representative on program teams, providing strategic input to program-level decision-making
- Lead interpretation of biomarker and clinical datasets, translating findings into clear, actionable recommendations for stakeholders
- Mentor biomarker scientists and support publications, presentations, external collaborations, and expert interactions
Privacy & handoff
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