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Postdoctoral Research Fellow, BioMedicine Design

Pfizer · San Diego, CA

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ResearchFull-time$65k–$108kCompany career page

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Role summary

Pfizer seeks a Ph.D.-level postdoctoral researcher to advance T cell engager development in the BioMedicine Design group at La Jolla. The fellow will integrate protein engineering, cell biology, and immunology to optimize therapeutic candidates and prepare for early-stage drug discovery roles.

What they're looking for

  • Ph.D. in cancer biology, immunology, molecular/cellular biology, biochemistry, or related discipline
  • Less than 2 years postdoctoral experience; commitment to 2–4 year full-time fellowship
  • At least one first-author publication in high-quality specialty or general journals
  • Proficiency in molecular cloning, protein expression/purification, mammalian cell culture, and flow cytometry
  • Strong technical rigor in experimental design, data analysis, and scientific communication
  • Prior experience with antibody discovery, protein engineering, or display technologies (yeast/phage) preferred
  • Experience with bispecific antibodies or T cell engagers a plus

What you'll be doing

  • Design and construct experimental systems to investigate target biology and mechanism of action
  • Develop and execute cell-based assays to screen, rank, and optimize therapeutic molecules
  • Conduct literature reviews to formulate testable hypotheses and identify research gaps
  • Present data at internal meetings and make evidence-driven decisions on project direction
  • Collaborate with interdisciplinary research teams on creative therapeutic discovery approaches

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