Associate Director, Global Health Economics & Outcomes Research (RWE)

Madrigal Pharmaceuticals · Conshohocken -, PA

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BiometricsFull-time$185k–$215kCompany career page

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Role summary

Madrigal Pharmaceuticals seeks an Associate Director to lead real-world evidence and health economics research supporting global patient access strategies for its MASH portfolio. The role combines evidence generation, regulatory support, and cross-functional collaboration to demonstrate medicine value and optimize reimbursement outcomes.

What they're looking for

Graduate degree in biostatistics, public health, epidemiology, or related field
10–12+ years of experience in health economics, outcomes research, or real-world evidence
Advanced R programming proficiency with version control tools and cloud platforms (Posit Workbench, Databricks)
Expertise in statistical methodologies: propensity score matching, IPTW, Cox regression, causal inference
Experience designing and executing observational, pragmatic, and implementation science studies
Knowledge of FDA and EMA regulatory guidance for real-world evidence submissions
Ability to work across global time zones and travel up to 30% for conferences and meetings

What you'll be doing

Design, build, and maintain internal data warehouses and analytical pipelines using R, SQL, and Python
Execute rapid and protocol-driven real-world studies including retrospective, prospective, pragmatic, and implementation science research
Collaborate with clinical, regulatory, access, and commercial teams to inform evidence strategy across product lifecycle
Ensure RWE studies meet FDA and EMA regulatory standards for label expansion and health technology assessment submissions
Present findings at scientific conferences and publish in peer-reviewed journals

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