Analytical Principal Research Scientist
Vertex Pharmaceuticals · Boston, MA
ResearchFull-time$141k–$211kCompany career page
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Role summary
Vertex Pharmaceuticals seeks a Principal Research Scientist to lead the Dissolution Team within Formulation Development. This role combines scientific expertise in analytical chemistry with team leadership, driving innovation in drug formulation and regulatory compliance while mentoring team members in a fast-paced environment.
What they're looking for
- Ph.D. in Chemistry, Chemical Engineering, or Pharmaceutical Chemistry with 4-7 years experience
- Master's degree with 7+ years experience, or Bachelor's with 10+ years experience
- Expertise in dissolution methods, analytical validation, and ICH/FDA compliance
- Leadership and mentoring capabilities with demonstrated team collaboration skills
- Strong written and verbal communication skills for cross-functional engagement
- Problem-solving ability and commitment to continuous learning in analytical science
What you'll be doing
- Lead dissolution team, mentor members, and foster collaborative, high-performing culture aligned with company values
- Design and execute dissolution studies; justify method parameters and specifications for formulation development
- Author regulatory submissions and develop ICH/FDA-compliant validation protocols for late-stage programs
- Identify critical analytical factors and parameters essential for robust method development and validation
- Ensure compliance with regulatory guidelines and contribute to standard operating procedures
Privacy & handoff
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